OS Therapies, a clinical stage biopharmaceutical company, is at the forefront of developing innovative treatments for Osteosarcoma (OS), breast cancer and other solid tumors. With a dedicated focus on addressing the unmet need for new cancer treatments in children and young adults, the company is making significant strides in tackling the complexities of OS, a rare but aggressive bone cancer predominantly affecting individuals under 40 years of age.

The company's primary initiative revolves around its lead product candidate, OST-HER2 (OST31-164), which is poised to revolutionize the treatment landscape for OS, breast cancer, and other HER2 expressing cancers. This innovative immunotherapy leverages a genetically modified strain of Listeria monocytogenes to specifically target cancer cells that express HER2 p, a promising approach in the fight against cancer that is complementary to HER2 antibody therapy such as Herceptin®. Notably, OST-HER2 is distinct in the current landscape, as there have been no new treatments approved by the FDA for OS in over 40 years.

In addition to OST-HER2, OS Therapies is expanding its impact with the OST-Tunable Antibody Drug Conjugate (OST-tADC) platform. This cutting-edge technology represents a next-generation approach in antibody-drug conjugates (ADCs), featuring tunable pH-sensitive silicone linkers (SiLinkers™) and the potential to deliver a range of payloads, including antibodies, chemotherapeutics, and mRNA treatments. The OST-tADC platform is being developed to target solid tumors.